Research Interests

1. Develop novel malignant tumor models to investigate tumor clonal evolution and cancer cell plasticity.

2. Develop efficacy evaluation indicators to explore rational drug combinations and precision medicine.

3. Develop new biologics and establish evaluation systems for their efficacy evaluation.

Research Topics

1. Non-genetic mechamism of tumor heterogeneity on tumor dissemination and drug resistance

2. Develop novel extranodal lymphoma models and explore the precise treatment strategies

Frontiers in Immunology, 2023; Frontiers in Oncology, 2023

3. Develop the OtR model and explore the precise treatment strategies

Frontiers in Pharmacology, 2024

4. Discovery and efficacy evaluation of novel synthetic lethal and novel drug combinations

iScience, 2024

5. Development and efficacy evaluation of novel biological drugs and novel gene therapies

Journal of Biological Chemistry, 2025