硕士研究生导师，讲师，资格副主任药师。主要从事代谢重塑在肿瘤演进及治疗靶点挖掘中的机制研究，以“代谢物-蛋白质翻译后修饰-肿瘤表型”为研究主线，重点解析多胺、单胺类神经递质、支链氨基酸等代谢物调控肿瘤发生、转移、复发耐药及免疫微环境的分子机制，并据此发现新的治疗靶点与干预策略。以第一/通讯作者在 Acta Pharm Sin B、Cell Commun Signal、Front Microbiol 等期刊发表论文多篇；主持国家自然科学基金青年项目、江苏省自然科学基金青年项目，入选镇江市“金山英才”医学领域高层次人才引进项目、镇江市青年科技人才托举工程,江苏省杰出医学领军人才团队核心成员。

招生方向

  本人招收药学、药理学方向硕士研究生，欢迎对肿瘤代谢与靶点发现感兴趣的同学报考。

科研和人才项目

1. 国家自然科学基金青年项目，2026.01-2028.12

2. 江苏省自然科学基金青年项目，2025.08-2028.08

3. 镇江市“金山英才”医学领域高层次人才引进项目，2024.12-2027.12

4. 镇江市青年科技人才托举工程项目，2025.07-2027.06

代表性论文

1. Feng D, Zhang J, Niu HM, Zheng XX, Jia MQ, Lu QQ, Wang J, Guo WX, Sun Q, Yuan HQ*, Lou HX*. Spermidine inactivates proteasome activity and enhances ferroptosis in prostate cancer. Acta Pharm Sin B （IF: 14.6）. 2025;15(4):2095-2113.

2. Ding XY, Liu HL, Zhang WR, Shen J, Zhang YT, Zhao DN, Guo MJ, Yuan X, Wang X*, Feng D*. Neurotransmitters in cancer: how receptor signaling and posttranslational modifications modulate tumor progression and offer new therapeutic targets. 

Cell Commun Signal （IF: 11.6）. 2026. doi: 10.1186/s12964-026-02998-7.

3. Wang ZR, Zeng C, Yan ZY, Xu ZF*, Feng D*. Dual-probe genome mining identifies citrulassin N, a novel citrullinemodified lasso peptide from Streptomyces sp. NAX00255. Front Microbiol. 2026. doi: 10.3389/fmicb.2026.1786444.

4. Zhang W, Shen J, Ding X, Liu H, Wang X*, Feng D*. Branched-chain amino acid transaminases as promising targets in tumor therapy. Front Cell Dev Biol. 2026. doi: 10.3389/fcell.2026.1712076.

5. Liu HL, Zuo H, Ding XY, Tang HW, Pu X, Liu MF, Zhang YT, Zhao DN, Guo MJ, Shen J, Zhang WR, Yuan X*, Feng D*, Wang X*. C5aR1-positive PMN-MDSC-induced angiogenesis limits the efficacy of radiotherapy combined with Anti-PD-1 immunotherapy. Cell Commun Signal （IF: 11.6）. 2026. doi: 10.1186/s12964-026-03178-3.

6. Zhang YT, Guo MJ, Zhao DN, Liu HL, Ding XY,  Yuan X, Jiang Y*, Feng D*, Wang X*. Neutrophil metabolic heterogeneity as a noveltarget in diseases.  Cell Commun Signal （IF: 11.6）. 2026. doi: 10.1186/s12964-026-03112-7.

7. Feng D, Tan L, Qiu L, Ju F, Kuang QX, Chen JF, Li XN, Gu YC, Guo DL*, Deng Y*. Three new polyketides produced by Penicillium crustosum, a mycoparasitic fungus from Ophiocordyceps sinensis. Phytochemistry Letters. 2020;36:150-155.